The night featured duets from Mickey Guyton and Gladys Knight, a new song from Kelsea Ballerini and Paul Klein, Miranda Lambert around a campfire and so much more.
Gabby Barrett won Female Video of the Year while Kane Brown won Male Video of the Year.
Isbell's 400 Unit, Drive-By Truckers, Lucinda Williams, and more will perform.
More artists are heading back on the road this summer
She's a 60s folk singer, a 70s disco queen and an 80s punk rocker in the visual for 'It's Cause I Am'.
Three cheers to the new Opry NextStage Artist.
